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FINNELL, RICHARD
One or more keywords matched the following items that are connected to FINNELL, RICHARD
Item TypeName
Concept Valproic Acid
Academic Article Teratogenicity of valproate conjugates with anticonvulsant activity in mice.
Academic Article Lack of concordance between heat shock proteins and the development of tolerance to teratogen-induced neural tube defects.
Academic Article Stereoselective pharmacokinetic analysis of valnoctamide, a CNS-active chiral amide analogue of valproic acid, in dogs, rats, and mice.
Academic Article Enantioselective pharmacodynamic and pharmacokinetic analysis of two chiral CNS-active carbamate derivatives of valproic acid.
Academic Article Valproic acid-induced changes in gene expression during neurulation in a mouse model.
Academic Article Anticonvulsant profile and teratogenicity of 3,3-dimethylbutanoylurea: a potential for a second generation drug to valproic acid.
Academic Article Comparative pharmacodynamic and pharmacokinetic analysis of two anticonvulsant halo derivatives of 2,2,3,3-tetramethylcyclopropanecarboxamide, an amide of a cyclic analog of valproic acid.
Academic Article Genetic basis of susceptibility to environmentally induced neural tube defects.
Academic Article Stereoselective pharmacodynamic and pharmacokinetic analysis of sec-Butylpropylacetamide (SPD), a new CNS-active derivative of valproic acid with unique activity against status epilepticus.
Academic Article Stereoselective pharmacokinetics and pharmacodynamics of propylisopropyl acetamide, a CNS-active chiral amide analog of valproic acid.
Academic Article Common hierarchies of susceptibility to the induction of neural tube defects in mouse embryos by valproic acid and its 4-propyl-4-pentenoic acid metabolite.
Academic Article Strain-dependent alterations in the expression of folate pathway genes following teratogenic exposure to valproic acid in a mouse model.
Academic Article Evaluation of stereoselective anticonvulsant, teratogenic, and pharmacokinetic profile of valnoctylurea (capuride): a chiral stereoisomer of valproic acid urea derivative.
Academic Article Valproic acid-induced skeletal malformations: associated gene expression cascades.
Academic Article Evaluation of the antiallodynic, teratogenic and pharmacokinetic profile of stereoisomers of valnoctamide, an amide derivative of a chiral isomer of valproic acid.
Academic Article Molecular basis of environmentally induced birth defects.
Academic Article Mapping a chromosomal locus for valproic acid-induced exencephaly in mice.
Academic Article Design and pharmacological activity of glycinamide and N-methoxy amide derivatives of analogs and constitutional isomers of valproic acid.
Academic Article Brief report novel mechanism for valproate-induced teratogenicity.
Academic Article Potent anticonvulsant urea derivatives of constitutional isomers of valproic acid.
Academic Article Valproic acid-induced alterations in growth and neurotrophic factor gene expression in murine embryos [corrected].
Academic Article Preclinical evaluation of 2,2,3,3-tetramethylcyclopropanecarbonyl-urea, a novel, second generation to valproic acid, antiepileptic drug.
Academic Article In utero antiepileptic drug exposure: fetal death and malformations.
Academic Article Ribonucleotide reductase subunit R1: a gene conferring sensitivity to valproic acid-induced neural tube defects in mice.
Academic Article Characterization of the anticonvulsant profile and enantioselective pharmacokinetics of the chiral valproylamide propylisopropyl acetamide in rodents.
Academic Article Metabolite profiling of whole murine embryos reveals metabolic perturbations associated with maternal valproate-induced neural tube closure defects.
Academic Article Alpha-fluoro-2,2,3,3-tetramethylcyclopropanecarboxamide, a novel potent anticonvulsant derivative of a cyclic analogue of valproic acid.
Academic Article Anticonvulsant activity, neural tube defect induction, mutagenicity and pharmacokinetics of a new potent antiepileptic drug, N-methoxy-2,2,3,3-tetramethylcyclopropane carboxamide.
Academic Article Gas chromatographic determination of novel valproyl taurinamide derivatives in mouse and dog plasma.
Academic Article Practice parameter update: management issues for women with epilepsy--focus on pregnancy (an evidence-based review): teratogenesis and perinatal outcomes: report of the Quality Standards Subcommittee and Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and American Epilepsy Society.
Academic Article Functional regulation of P-glycoprotein at the blood-brain barrier in proton-coupled folate transporter (PCFT) mutant mice.
Academic Article Myo-inositol enhances teratogenicity of valproic acid in the mouse.
Academic Article Valproate-induced neural tube defects in folate-binding protein-2 (Folbp2) knockout mice.
Academic Article Pharmacodynamic and pharmacokinetic analysis of CNS-active constitutional isomers of valnoctamide and sec-butylpropylacetamide--Amide derivatives of valproic acid.
Academic Article Seizure control following administration of anticonvulsant drugs in the quaking mouse.
Academic Article Management issues for women with epilepsy-Focus on pregnancy (an evidence-based review): II. Teratogenesis and perinatal outcomes: Report of the Quality Standards Subcommittee and Therapeutics and Technology Subcommittee of the American Academy of Neurology and the American Epilepsy Society.
Academic Article Anticonvulsant activity, teratogenicity and pharmacokinetics of novel valproyltaurinamide derivatives in mice.
Academic Article Stereoselective anticonvulsant and pharmacokinetic analysis of valnoctamide, a CNS-active derivative of valproic acid with low teratogenic potential.
Academic Article Neural tube defects, folate, and immune modulation.
Academic Article Teratogenicity of valproic acid and its constitutional isomer, amide derivative valnoctamide in mice.
Grant INTERVENTION STRATEGIES FOR NON-FOLATE RESPONSIVE NEURAL TUBE DEFECTS
Grant Genetic Regulation of Valproic Acid Teratogenicity
Academic Article Chromatin Imbalance as the Vertex Between Fetal Valproate Syndrome and Chromatinopathies.
Academic Article Embryonic Hypotaurine Levels Contribute to Strain-Dependent Susceptibility in Mouse Models of Valproate-Induced Neural Tube Defects.
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  • Valproic Acid